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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Toxic epidermal necrolysis ： ウィキペディア英語版 Toxic epidermal necrolysis Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a rare, life-threatening skin condition that is usually caused by a reaction to drugs.〔Garra, GP (2007). "(Toxic Epidermal Necrolysis )". Emedicine.com. Retrieved on December 13, 2007.〕 The disease causes the top layer of skin (the epidermis) to detach from the lower layers of the skin (the dermis), all over the body, leaving the body susceptible to severe infection. The mortality rate ranges from 25-30%, and death usually occurs as a result of sepsis and subsequent multiorgan system failure. Treatment primarily involves discontinuing the use of causative agent(s), and supportive care in either the intensive care unit or burn unit of a hospital.〔http://www.genome.gov/27560487〕 The incidence of TEN is between 0.4 and 1.9 cases per million each year. TEN exists on a continuum with Stevens–Johnson syndrome (SJS). The condition is called TEN when >30% of the body surface area is involved. It is called SJS when <10% of body surface area is involved. The intermediate form, with 10 to 30 percent body surface area involvement, is called "SJS/TEN." Although there was initially debate about whether TEN and SJS fall on a spectrum of disease that includes erythema multiforme (EM), they are now considered separate conditions.〔 ==Signs and symptoms== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Toxic epidermal necrolysis」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.